CE Certified Plant Extract Manufacturer & Exporter

Our production operations are conducted under NSF/ANSI 455-2 Dietary Supplement cGMP, ISO 22000:2018 food safety management systems, and HACCP Codex Alimentarius guidelines. For European buyers, we provide exhaustive batch dossiers including Certificate of Analysis (COA) with active marker assay verification by HPLC/UV, heavy metal analysis via ICP-MS conforming to Regulation (EU) 2023/915, pesticide residue screening covering over 400 compounds via GC-MS/MS under Regulation (EC) No 396/2005, polycyclic aromatic hydrocarbon (PAH4) limits under Regulation (EU) No 2015/1933, and certified non-irradiation / non-ETO statements.

Contaminant prevention starts at the raw agricultural intake. ESNO Biotech operates under strict Good Agricultural and Collection Practices (GACP) to prevent inadvertent co-harvesting of weed species known to contain pyrrolizidine alkaloids (PA) such as Senecioneae and Boraginaceae, and tropane alkaloids (atropine, scopolamine). Each incoming herb lot is quarantined and tested using high-sensitivity LC-MS/MS against the low ppb limits mandated by Regulation (EU) 2020/2040. In addition, our cleanrooms use high-temperature short-time (HTST) steam sterilization or clean ozone treatment—strictly avoiding ethylene oxide (EtO) across all processes.

We accommodate both fast-scaling digital brands and multinational pharmaceutical distributors. For catalog stock hard-capsule formulations (such as our standardized Lion's Mane, Rhodiola Rosea 500mg, and Myo-Inositol complexes), our minimum order quantities (MOQ) start from as low as 100 to 500 bottled or boxed units. For fully customized OEM/ODM formulations involving proprietary dry blending, custom tooling, custom color HPMC shells, and unique secondary packaging, MOQs generally begin at 1,000 to 3,000 retail units. Bulk active botanical extracts are available starting from 1 kg trial sample lots to multi-ton commercial container shipments.

Yes. Our in-house R&D department has designed and commercialized more than 400 custom dietary formulations. We evaluate physical particle morphology, bulk density, flowability (Carr's Index and Hausner Ratio), hygroscopic tendencies, and chemical compatibility between active phytochemicals and excipients. If you require zero synthetic additives, we formulate using organic rice hull extract (Nu-RICE / Nu-FLOW) and natural plant fibers. We also execute accelerated stability testing (40°C ± 2°C / 75% RH ± 5% RH over 6 months) to determine precise expiration dating, packaging moisture barrier integrity, and active preservation.

Custom bench-top pilot sampling and formulation prototypes are typically prepared and dispatched via DHL/FedEx within 5 to 7 working days. Following client sign-off on analytical specifications and finished packaging artwork, mass encapsulation, bottling, induction sealing, labeling, and lot coding are concluded within 15 to 25 business days. Commercial exports can be dispatched via air freight (4–7 transit days door-to-airport/door-to-door) or sea freight (20–35 days to European/North American base ports) accompanied by complete customs clearance paperwork including Bill of Lading, Certificate of Origin, and packing lists.

Adulteration is a significant risk in the botanical trade, particularly in high-value categories like Rhodiola, Saw Palmetto, Shilajit, and Ginkgo. ESNO Biotech combats economically motivated adulteration via a multi-tiered identity verification matrix: High-Performance Thin-Layer Chromatography (HPTLC) for profile identification against authenticated pharmacopoeial botanical reference standards, coupled with HPLC active marker ratio verification (for example, monitoring the balance of rosavins to salidroside in authentic Rhodiola rosea versus Rhodiola crenulata). In addition, we utilize specific isotopic or mass-spec testing to detect non-botanical adulteration or exogenous active enrichment.