Step 01
Raw Material
Identity verification, organoleptic checks, and analytical quarantine before release into formulation.
NSF 455-2 & ISO 22000Stringent dietary supplement GMP audit compliance
Full Process TraceabilityQuarantine, lot tracking, and batch record retention
Internal Analytical LabMicrobial assay, potency, and loss-on-drying verification
TÜV Rheinland VerifiedOn-site audited physical facilities and export capacity
Standard Operating Procedures
The 10-Stage GMP Production Workflow
Every private label formula manufactured by Shaanxi ESNO Biotech Co., Ltd. follows a validated, documented path from raw material quarantine to finished export cartoning.
Step 02
Mixing
V-shell and high-shear three-dimensional blending to guarantee active ingredient uniformity per unit.
Step 03
Pelletizing
Wet and dry granulation technology optimizing bulk powder flowability and tablet compressibility.
Step 04
Tableting
Rotary press compression with continuous in-line sampling for tablet hardness, weight, and friability.
Step 05
Coating
Aqueous enteric and film coating for oxygen barrier protection, taste masking, and brand color alignment.
Step 06
Filling
High-precision automatic encapsulation and volumetric powder dosing in controlled clean environments.
Step 07
Sphere Pressing
Specialized molding for unique delivery formats, concentrated shilajit balls, and novel botanicals.
Step 08
Packing 1
Primary containment including automated bottle filling, induction sealing, and blister foil sealing.
Step 09
Packing 2
Precision label application, tamper-evident shrink sleeve application, and inkjet batch/expiry coding.
Step 10
Packing 3
Outer master cartoning, corner reinforcement, and palletizing engineered for rigorous global freight.
Engineered Automation
Advanced Equipment & High-Output Lines
Our workshop is equipped with high-speed automated machinery engineered to meet stringent cleanroom tolerances, reduce human intervention, and maintain batch consistency.
Uniform Blending
Mixing Machine
Sanitary stainless-steel industrial blender for dry powder premixes, herbal extracts, and mineral active complexes.
Sanitary SS316LCross-Contamination ProofBatch Homogeneity
Granulation Control
Pelletizing Machine
Continuous granulator regulating granule density, moisture tolerance, and flow properties for high-speed tableting.
Uniform Particle SizeHigh Density GranulesLow Friability
High-Speed Compression
Tableting Machine
Multi-station rotary compression press with automated weight regulation, producing round, oblong, and chewable formats.
Pressure MonitoringCustom EmbossingDual-Discharge
Intelligent Film Pan
Coating Machine
Perforated pan coater equipped with automated spray nozzles for even application of enteric, film, and aesthetic color coatings.
Micro-AtomizationThermal Air ControlZero Edge Peeling
Form-Fill-Seal
Packing Machine
Vertical automated stick pack and multi-lane sachet packaging machinery for functional drink powders and soluble botanicals.
Multi-Lane PackagingNitrogen FlushingHermetic Sealing
Integrated Bottling
Automatic Packaging Machine
High-speed line integrating bottle unscrambling, electronic counting, desiccant insertion, capping, and tamper sealing.
Optical CounterTorque CappingInduction Sealing
Precision Dosing
Filling Machine
Automated hard capsule filler handling sizes 000 through 4, with tamping pin mechanisms ensuring weight consistency.
Capsule Sizes 000-4Weight Variance <2%Dust-Tight System
Blister Packaging
Aluminum Plastic Packing Machine
Alu-Alu and Alu-PVC blister packer providing moisture-proof, pharmaceutical-grade individual dose barriers.
High Moisture BarrierPush-Through FoilIn-Line Perforation
Novel Dosage Formation
Sphere Pressing Machine
Calibrated pressing equipment dedicated to traditional ball formations, concentrated herbal drops, and solid resin spheres.
Direct MoldingDense Core StructureCustom Geometry
In-House Quality Assurance
Analytical Laboratory & In-Process Testing
Shaanxi ESNO Biotech Co., Ltd. operates a dedicated quality control laboratory where raw ingredients, in-process blends, and finished batches undergo physical, chemical, and microbiological verification prior to release.
Incubator
Precision temperature-controlled incubation chambers for microbiological assays, total plate counts (TPC), yeast & mold enumeration, and pathogen screen testing.
Drying Box
Constant-temperature analytical drying ovens utilized for accurate loss-on-drying (LOD) moisture content analysis and accelerated thermal stability studies.
Electronic Balance
Certified 0.1 mg micro-analytical balances ensuring micro-dosing precision, reference standard preparation, and weight variance verification across all batches.
Request a Facility Audit or Custom Quote
Contact the engineering and sales team at Shaanxi ESNO Biotech Co., Ltd. to discuss batch pilot runs, specification matching, or factory compliance documentation.