NSF 455-2 GMP · ISO 22000 · HACCP [email protected]
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Shaanxi ESNO Biotech Co., Ltd. Manufacturing Facility

Company Profile

A Trusted OEM/ODM Partner for Global Dietary Supplements, Botanical Actives & Formulation Excellence

Enterprise Overview

Shaanxi ESNO Biotech Co., Ltd.

Founded in 2006, Shaanxi ESNO Biotech Co., Ltd. is a high-technology manufacturing enterprise specialized in the research, custom formulation, and precision manufacturing of dietary supplements, botanical extracts, and functional foods.

Headquartered in the High-Tech Zone of Xi'an, Shaanxi, our facilities operate under internationally audited quality control frameworks including NSF 455-2 GMP, ISO 22000, HACCP, Halal, Kosher, EU Organic, and USDA Organic standards. We supply brand owners, retail chains, and e-commerce supplement leaders across more than 100 countries.

19+ Years Nutraceutical Formulation & Manufacturing Experience
100+ Countries Global Supply Footprint & Regulatory Compliance
400+ Formulations Developed for Global Dietary Brands
TÜV Rheinland On-Site Verified Facility & Supply Chain Reliability

Verified Supplier Evaluation

Audited by TÜV Rheinland
98.6%
On-Time Dispatch Rate
≤ 2h
Average Response Time
4.5 / 5.0
Buyer Rating (48+ Reviews)
Full Customization on Demand
Rapid Sampling in 3–7 Days
Batch-Specific COA Documentation
On-Site Material & Final Inspection
119+ New R&D Products Annually
Dedicated E-Commerce Logistics
Manufacturing Transparency

Step-by-Step Production Process

Every batch produced by Shaanxi ESNO Biotech Co., Ltd. follows standardized operating procedures inside GMP-compliant cleanrooms to guarantee purity, dosage accuracy, and batch-to-batch stability.

STEP 01 Raw Material Inspection at Shaanxi ESNO Biotech

Raw Material

Identity verification, assay purity testing, and strict quarantine before material release.

STEP 02 Precision Powder Mixing

Mixing

Three-dimensional blending of active ingredients and excipients ensuring uniform potency.

STEP 03 Pelletizing and Granulation

Pelletizing

Granulation process optimizing flow characteristics and compression compatibility.

STEP 04 Tablet Compression Process

Tableting

High-speed rotary compression with real-time weight variation and friability controls.

STEP 05 Aqueous and Film Coating

Coating

Functional film or sugar coating for enteric protection, moisture barrier, and taste masking.

STEP 06 Precision Capsule and Bottle Filling

Filling

Automated dosing into hard gelatin, vegan HPMC capsules, or high-speed bottling lines.

STEP 07 Sphere and Specialty Compression

Sphere Pressing

Specialized sphere forming and resin ball molding for modern functional supplement delivery.

STEP 08 Primary Bottle Packaging

Packing (Primary)

Desiccant insertion, induction foil sealing, child-resistant capping, and security seals.

STEP 09 Labeling and Secondary Box Packing

Packing (Secondary)

High-precision wrap-around labeling with automated batch number and expiry laser printing.

STEP 10 Export Packaging and Palletizing

Packing (Export)

Heavy-duty corrugated master cartons, moisture-barrier lining, and corner-protected palletizing.

Advanced Equipment

Dedicated Processing Machinery

Our workshop integrates automated high-speed machinery designed to handle small trial runs as well as continuous multi-million unit commercial manufacturing.

MACHINERY Industrial Mixing Machine

Mixing Machine

Stainless steel 316L high-shear and ribbon blenders ensuring absolute compound dispersion.

MACHINERY Fluid Bed Pelletizing Machine

Pelletizing Machine

Oscillating and fluid-bed granulators configured for high-density, low-dust granules.

MACHINERY Rotary Tableting Machine

Tableting Machine

Multi-station rotary presses equipped with tooling for round, oblong, and embossed custom tablets.

MACHINERY Perforated Coating Machine

Coating Machine

Automated perforated pan coating systems providing uniform film layer and color matching.

MACHINERY Stick Pack and Sachet Packing Machine

Packing Machine

Multi-lane powder stick pack and 3-side/4-side sachet forming, filling, and sealing line.

MACHINERY Automatic Packaging Machine Line

Automatic Packaging Machine

Complete robotic line handling electronic counting, bottle unscrambling, and tamper-proofing.

MACHINERY Precision Liquid and Capsule Filling Machine

Filling Machine

Volumetric and gravimetric dosing units for high-precision powder, liquid, and paste filling.

MACHINERY Aluminum Plastic Blister Packing Machine

Aluminum Plastic Packing Machine

Alu-PVC and Alu-Alu thermoforming blister packaging ensuring maximum shelf-life stability.

MACHINERY Industrial Sphere Pressing Machine

Sphere Pressing Machine

Specialty equipment customized for solid herbal resin drops, sphere compression, and novel formats.

Analytical Testing & QC

In-House Testing Laboratory

Our dedicated quality assurance and analytical testing facility rigorously screens raw materials, in-process intermediates, and finished goods to ensure full regulatory and chemical compliance.

QC TESTING Microbiology Constant Temperature Incubator

Incubator

Precision microbial incubators for Total Aerobic Microbial Count (TAMC), Yeast & Mold (TYMC), and pathogen-free confirmation.

QC TESTING Thermostatic Drying Box

Drying Box

Controlled thermostatic drying chambers used for Loss on Drying (LOD), residual moisture checks, and stability stress evaluations.

QC TESTING High-Precision Electronic Analytical Balance

Electronic Balance

Calibrated four-decimal analytical electronic balances ensuring exact standard preparations, assays, and weight uniformity.

Main Export Markets

Shaanxi ESNO Biotech Co., Ltd. possesses comprehensive international shipping and documentation experience, exporting compliant supplements to all major global continents.

North America (USA, Canada)45%
Western Europe (UK, Germany, France, etc.)19%
Oceania (Australia, New Zealand)15%
Southeast Asia9%
Middle East & Other Regions12%

Customization & Export Services

We support procurement teams and brand owners with end-to-end private label execution and export handling.

Formula Development & Reverse Engineering Custom blend design, active compound optimization, flavoring, and stability verification.
Regulatory & Label Compliance Review FDA supplement facts styling, EU labeling guidelines, allergen declarations, and packaging review.
International Shipping & Customs Clearance Fast dispatch through major ports (Shanghai, Tianjin) via air express, DDP to Amazon FBA, or ocean freight.
International Audits

Quality Assurance & Compliance Standards

Our manufacturing and processing lines maintain verified certifications with regular independent third-party audits.

NSF 455-2 GMP

Good Manufacturing Practice standard for dietary supplements verifying sanitation, traceability, and facility control.

ISO 22000:2018

Food Safety Management System covering the complete processing chain from raw material intake to packaging.

HACCP Certified

Hazard Analysis Critical Control Point system systematically preventing biological, physical, and chemical hazards.

EU & USDA Organic

Verified organic processing for herbal extracts and superfood ingredients free of synthetic additives.

HALAL & Kosher

Compliant with Islamic dietary laws and Jewish kosher regulations for broad international consumer eligibility.

COA With Every Batch

Every lot is tested for assay, heavy metals (Pb, As, Cd, Hg), and microbial limits before dispatch.

Ready to Develop Your Private Label Supplement?

Contact the engineering and manufacturing team at Shaanxi ESNO Biotech Co., Ltd. for formula consultation, custom quoting, and sample testing.

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