Manufactured under NSF 455-2 GMP and ISO 22000 protocols with batch-specific Certificates of Analysis (COA) compliant with Spanish AESAN and EFSA botanical parameters.
The Zaragoza metropolitan zone, anchored by Plataforma Logística de Zaragoza (PLA-ZA), represents the preeminent multimodal transport infrastructure in the Iberian Peninsula. Connecting Catalonia, the Basque Country, Madrid, and the French border via high-capacity rail and motorway networks (A-2, AP-68), Zaragoza has evolved far beyond traditional logistics into a primary processing and formulation hub for agricultural, functional food, and veterinary manufacturing.
Within this vibrant industrial ecosystem, demand for CE certified and EU-compliant carotenoid extracts has escalated rapidly. Zaragoza-based procurement directors, contract manufacturers (CMOs), and private-label distributors require high-density, oxygen-stabilized, and light-shielded carotenoids—predominantly Natural Beta-Carotene, Tagetes Lutein & Zeaxanthin, Tomato-Derived Lycopene, and Haematococcus pluvialis Astaxanthin. Because European botanical imports are heavily governed by EFSA hygiene controls, heavy-metal restrictions (Commission Regulation EU 2023/915), and residual solvent thresholds (Directive 2009/32/EC), working directly with an audited primary extraction manufacturer like Shaanxi ESNO Biotech Co., Ltd. guarantees strict batch repeatability, continuous physical auditability, and immediate customs clearing through Valencia or Barcelona maritime freight hubs directly into Aragón’s customs bonded terminals.
Formulation of macular health softgels and visual fatigue hard capsules for senior demographics throughout Spain. High-potency Marigold-derived Lutein (5%-80% HPLC/UV) and Zeaxanthin powder blends formulated alongside Zinc, Vitamin D3, and anthocyanins.
Aragón’s extensive beverage, confectionery, and dairy processors utilize oil-dispersible and cold-water-soluble (CWS) Beta-Carotene formulations as natural yellow-to-orange clean-label colorants to displace artificial synthetic dyes (Tartrazine E102, Sunset Yellow E110).
The Ebro Valley livestock sector sources saponified Marigold lutein and natural beta-carotene premixes to guarantee high-bioavailability yolk and broiler skin pigmentation, meeting stringent non-GMO and residue-free EU feed additives benchmarks (Regulation EC No 1831/2003).
Selecting carotenoid ingredients requires detailed chromatographic transparency. Carotenoids are highly conjugated isoprenoid polyenes sensitive to photo-oxidation, thermal degradation, and isomerization from all-trans to less bioactive cis configurations. Below is our standard analytical baseline verified per production lot prior to dispatch:
| Active Ingredient | Standardized Assay | Extraction Vehicle | Physical Form | EU Compliance Status | Typical Zaragoza Application |
|---|---|---|---|---|---|
| Natural Lutein | 5% to 80% (HPLC / UV) | Tagetes erecta L. | Free Powder / Beadlets / Oil | EFSA Compliant | Ophthalmic Supplements, Eye Drops |
| Lycopene | 5% to 98% (HPLC) | Solanum lycopersicum L. | Microencapsulated Beadlets / Oil Susp. | Novel Food Ready | Prostate Formulations, Anti-aging |
| Beta-Carotene | 1% CWS, 10% Beadlet, 30% Oil | Blakeslea trispora / Fermentation | Cold-Water Dispersible Beadlet | E160a(ii) Grade | Functional Beverages, Confectionery |
| Natural Astaxanthin | 2% to 10% (HPLC) | Haematococcus pluvialis | Oleoresin / Microencapsulated Powder | Novel Food Authorized | Sports Endurance, Dermocosmetic Care |
| Zeaxanthin | 5% to 60% (HPLC) | Marigold Flower Extract | Crystalline Powder / Beadlets | EFSA Compliant | Synergistic Blue-Light Defense |
Each analytical batch undergoes validated test sequences in our in-house ISO-calibrated laboratory. We verify lead (Pb < 2.0 ppm), cadmium (Cd < 1.0 ppm), mercury (Hg < 0.1 ppm), and inorganic arsenic (As < 1.0 ppm) via Inductively Coupled Plasma Mass Spectrometry (ICP-MS), accompanied by certified gas chromatography testing confirming zero residual chlorinated hydrocarbons or non-permitted extraction solvents.
Supplying the Spanish nutraceutical and pharmaceutical market entails strict compliance overseen domestically by the Agencia Española de Seguridad Alimentaria y Nutrición (AESAN) under the pan-European auspices of the European Food Safety Authority (EFSA). For professional purchasers in Zaragoza, three major technical hurdles consistently dictate commercial success:
Governing food supplement notifications in Spain. Carotenoid formulations must respect maximum permitted daily dosages while maintaining rigorous identity confirmation via HPLC fingerprinting.
Novel Food regulations governing high-potency microalgae extracts like Haematococcus pluvialis (Astaxanthin). Complete toxicological and genotoxicity qualification files are systematically maintained.
Zero ethylene oxide (EtO) tolerance and strict limits on hundreds of pesticide residues. Multi-residue screening via LC-MS/MS and GC-MS/MS guarantees frictionless entry through Spanish Border Inspection Posts (BIP).
Certified full organic compliance for eligible botanical derivatives, matching consumer demands across Zaragoza’s premium retail channels and specialized pharmacies.
Founded in 2006 in the botanical heartland of Xi'an, Shaanxi ESNO Biotech Co., Ltd. operates state-of-the-art cGMP extraction and dosage manufacturing facilities audited on-site by TÜV Rheinland. For over 19 years, our specialized engineers have bridged botanical chemistry and scalable formulation for more than 3,500 enterprise buyers across 100+ countries.
Unlike intermediate trading firms, ESNO Biotech operates an end-to-end quality system encompassing vacuum extraction, counter-current concentration, multi-stage column chromatography, spray drying, and cleanroom encapsulation. Holding NSF 455-2 GMP, ISO 22000, HACCP, and EU Organic standards, we offer Zaragoza buyers low-MOQ flexibility for novel product prototyping alongside multi-ton capacity for industrial baseline runs.
Positive-pressure HVAC environments with strictly monitored HEPA filtration, ensuring zero cross-contamination during active powder handling and blending.
Equipped with Shimadzu HPLC, GC-FID, atomic absorption, and stability chambers conducting real-time accelerated degradation studies for shelf-life validation.
High-speed rotary encapsulators and automated blister packaging lines capable of producing 1.2 million hard capsules and 800,000 gummies daily.
Technical and logistical queries commonly addressed during supplier qualification by Spanish procurement managers.
Every shipment destined for Aragón includes a complete commercial dossier: Signed Commercial Invoice, Packing List, Original Bill of Lading (or Express Telex Release), Certificate of Origin (Form A / REX compliant), Certificate of Analysis (COA) per batch, Non-GMO Declaration, Allergen Statement, and BSE/TSE Free Statement. We also supply raw material manufacturing flowcharts to facilitate expedited clearance through Spanish Aduanas (Customs).
Carotenoids are susceptible to photo-oxidation and thermal cleavage. We employ advanced microencapsulation technologies (starch-sodium octenyl succinate or gelatin matrices) formulated with food-grade antioxidants (mixed tocopherols, sodium ascorbate). Finished powders are vacuum-sealed inside multi-layer aluminum foil barrier bags flushed with dry nitrogen (N2) before insertion into fiber drums, ensuring 24-month stability at room temperature.
For established stock formulations in hard capsules (such as Saw Palmetto + Lycopene or Curcumin complexes), our MOQ begins at just 500 to 1,000 retail bottles. For fully bespoke custom active blends or specialized beadlet-filled HPMC capsules, project thresholds typically begin at 50,000 to 100,000 capsules, accommodating emerging Spanish nutraceutical start-ups as well as industrial contract packers.
Yes. All our botanical extracts strictly comply with Commission Regulation (EU) 2023/915 for maximum levels of contaminants (Lead < 2.0 mg/kg, Cadmium < 1.0 mg/kg, Mercury < 0.1 mg/kg) and Regulation (EC) 396/2005 regarding pesticide residues. Independent third-party verification reports from Eurofins or SGS are available upon contractual request.
Absolutely. Our regulatory affairs department assists your technical team with quantitative ingredient breakdowns, solvent residue data, microbiological limits, stability data, and packaging labeling reviews complying with European Regulation (EU) No 1169/2011 to streamline national notification in Spain.
Standard pilot samples and express courier consignments (via DHL/FedEx) arrive in Zaragoza within 4 to 6 business days. Commercial LCL or FCL ocean freight from Qingdao/Shanghai to Valencia or Barcelona averages 26 to 32 days transit, followed by 48-hour bonded overland freight delivery directly into PLA-ZA logistics warehouses.
Connect directly with ESNO Biotech's dedicated technical sales engineers. Receive comprehensive technical specifications, European compliance dossiers, pilot samples, and factory-direct volume pricing within 24 hours.