Years Botanical Formulation Expertise
Export Destinations Across The Americas & EU
Finished Batches Successfully Shipped
Proprietary Finished Supplement Formulas
Our NSF-audited facility produces batch-certified hard capsules, softgels, and botanical powders utilizing standardized active markers, calibrated particle size distributions, and complete traceability dossiers.
Meeting the operational criteria of US brand owners, third-party logistics fulfillment centers, and retailer technical standards through strict phytochemistry governance.
The US dietary supplement landscape is experiencing massive migration from simple single-entity leaf powders to standardized botanical phytocomplexes. Formulators targeting executive focus, neuro-protection, and stress resilience require precise quantification of secondary metabolites.
Our extraction methodologies preserve key markers such as total polyphenol ratios, adaptogenic withanolides, and chlorogenic acid fractions, resolving solubility challenges in stick packs and hard capsules alike.
Modern American consumers demand clean-label functional beverages and meal replacements fortified with bioactive leaf extracts (green tea, moringa, yerba mate, and olive leaf). The technical barrier has consistently been bitter astringency and clarity stability.
We deploy gentle membrane filtration, debittering resin columns, and micro-granulation. This provides US RTD beverage brands instant water solubility, visual clarity without sedimentation, and thermal stability during pasteurization cycles.
US topical brands governed by strict retailer clean lists (Sephora Clean, Credo) necessitate botanical extracts processed without toxic residual solvents such as hexane or benzene. Phenolic leaf extracts act as potent radical scavengers for skin longevity formulas.
Our hydroethanolic and subcritical water extraction techniques result in botanical active extracts that are decolorized where required, dermatologically validated, and fully compliant with California Proposition 65 limits.
Navigating the convergence of FDA regulatory pressures, Amazon dietary supplement compliance certifications, and consumer expectations for traceable purity.
The US market has structurally shifted due to updated Amazon seller compliance rules. All dietary supplement brands must present ISO/IEC 17025 accredited laboratory test results validating that the finished product matches label claims for active ingredient potency.
Shaanxi ESNO Biotech provides US brand partners with full testing dossiers, validating active phytochemical concentrations via HPLC, LC-MS/MS, and GC-MS prior to transpacific air or ocean dispatch.
Procurement teams across California, Utah, and Florida are abandoning unstandardized leaf powders due to uncontrolled natural variance. Standardized extract ratios (e.g., 10:1, 20:1, or 50% polyphenols) ensure clinical dose repeatability.
Every lot manufactured at ESNO Biotech undergoes validated fingerprinting to guarantee secondary metabolite markers remain steady across agricultural crop seasons.
Heavy metals (Lead, Arsenic, Cadmium, Mercury) present severe product liability risks under California Safe Drinking Water and Toxic Enforcement Act (Prop 65). We enforce strict raw leaf quarantine protocols.
Our raw material testing protocols eliminate risks prior to extraction, ensuring total heavy metal levels fall significantly below the strict 0.5 mcg/day lead threshold mandated for non-warning labeled US retail packaging.
Since 2006, Shaanxi ESNO Biotech Co., Ltd. has delivered integrated OEM/ODM contract manufacturing, bridging botanical raw material sourcing with certified finished dosage delivery.
Operating under verified NSF 455-2 GMP, ISO 22000, and HACCP frameworks. Cleanroom production lines audited on-site by TÜV Rheinland for maximum operational transparency.
Equipped with calibrated precision electronic balances, microbiological incubators, high-performance liquid chromatography (HPLC), and drying balance systems for real-time batch release verification.
From standardized bulk extracts to vegan HPMC capsules, pectin gummies, tablet compression, film coating, and single-serve powder stick packs, we manage the complete formulation chain.
Supporting burgeoning direct-to-consumer digital native brands with low initial production minimums starting at 100 to 500 units for standard stock formulas, scaling to multimillion-unit enterprise runs.
Direct technical and operational clarifications regarding regulatory compliance, documentation, customs clearance, and quality assurance.