High-Precision Contract Encapsulation for Global Nutraceutical Brands
From single active botanical extracts to complex multi-ingredient mineral formulations, Shaanxi ESNO Biotech Co., Ltd. delivers pharmaceutical-grade hard capsule manufacturing engineered for superior bio-accessibility and international compliance.
Clean-Label Shell Variety
Vegetable HPMC, organic pullulan, and pharmaceutical bovine/porcine gelatin. Free from titanium dioxide, artificial colors, and GMO excipients.
Flexible Size Options (#000–#4)
Full tooling versatility across sizes 000, 00, 0E, 0, 1, 2, 3, and 4. Precision dosing with micro-dosing capabilities down to 100 mg up to 1,200 mg per unit.
Full Regulatory Audit Support
Every commercial batch comes with HPLC/ICP-MS tested COA, heavy metal limits verification, microbiological safety assays, and stability data.
Rapid Pilot to Commercial Scale
Low MOQ private labeling from 100 retail bottles to multi-million capsule automated runs in pharmaceutical-grade ISO Class 8 cleanrooms.
Verified Capsule Formulations Ready for Private Label
Browse our popular encapsulated nutritional supplements. All formulas can be bottled, blistered, boxed, and labeled under your brand identity with custom potencies.
Creatine Monohydrate Capsules (3,000mg / 5,000mg)
Private Label 500mg Vitamin B12 Botanical Capsules
Magnesium Bisglycinate Capsules (400mg / 500mg)
Milk Thistle Standardized Silymarin 80% Capsules
OEM KSM-66® Ashwagandha Root Capsules 500mg
Lion's Mane (Hericium Erinaceus) Extract Capsules
NAD+ Booster & Resveratrol Synergy Capsules
Dual-Extracted Lion's Mane Mushroom 500mg Capsules
Certified Organic Hericium Erinaceus Vegan Capsules
Organic Red Reishi (Ganoderma Lucidum) Capsules
High Absorption Magnesium Glycinate 500mg Capsules
Turnkey Lion's Mane 60 Count Bottled Supplements
Lactobacillus Reuteri HR7 Probiotic Balance Capsules
Pure N-Acetyl L-Cysteine (NAC) 600mg Capsules
Vitamin D3 5000 IU + K2 (MK-7 75mcg) Complex Capsules
End-to-End Capsule Manufacturing Process
Every commercial batch follows our strict cGMP SOPs. View the real verified production milestones implemented inside Shaanxi ESNO Biotech Co., Ltd.'s cleanroom facility.
Raw Material
Spectroscopic identity verification, botanical assay qualification, and quarantine testing.
Mixing
V-cone and three-dimensional blending to achieve 99.8% coefficient of uniformity.
Pelletizing
Dry compaction and fluid-bed granulation ensuring optimal flowability and uniform fill density.
Tableting
Rotary compression lines for multi-layer core formulation and specialty dual-delivery options.
Coating
High-efficiency perforated coating drums for moisture barrier, taste masking, and gastro-resistance.
Filling
Tamping pin and dosator capsule filling machines with automated weight rejection controls.
Sphere Pressing
Specialty pellet and micro-sphere beadlet formation for delayed release combinations.
Packing 1 (Primary)
Automated electronic counting, desiccant insertion, induction foil sealing, and child-safe capping.
Packing 2 (Secondary)
Wrap-around labeling, batch laser coding, tamper-evident shrink sleeve, and unit cartoning.
Packing 3 (Export)
Heavy-duty corrugated master cartons, moisture-barrier wrap, and seaworthy palletizing.
High-Throughput Encapsulation & Packaging Machinery
Our workshop houses high-speed automated machinery engineered to minimize downtime, maximize batch uniformity, and prevent cross-contamination.
On-Site Quality Assurance Laboratory
Quality isn't inspected in at the end; it's engineered into every step. Our internal analytical laboratory conducts raw material testing, in-process verifications, and complete finished batch releases.
Constant Temperature Incubator
Employed for stringent microbiological testing: Aerobic Plate Counts, Yeast & Mold, Enterobacteria, Salmonella spp., and Staphylococcus aureus per USP/EP guidelines.
Precision Drying Box
Performs Loss on Drying (LOD) and moisture residue assays, ensuring active powder stability inside hygroscopic HPMC and gelatin shells to prevent brittleness or microbial growth.
Calibrated Electronic Balance
Four-decimal analytical weighing balances ensuring micrometric accuracy for reference standards, active ingredient titration, and weight variation testing per 100 capsules.
| Parameter | ESNO Biotech Standard Capabilities | Compliance & Verification |
|---|---|---|
| Capsule Shell Types | Vegetable HPMC (Kosher/Halal certified), Organic Pullulan, Bovine Gelatin, Delayed-Release Enteric Shells | USP <2040> / EP standards, Non-GMO project compliant |
| Available Sizes & Fills | #000 (1000–1200mg), #00 (600–850mg), #0 (400–600mg), #1 (300–450mg), #2, #3, #4 | Dosing tolerance: ±2.5% automated weight check |
| Shell Colors & Branding | Clear, All-Natural Chlorophyll Green, Custom Pantone Two-Tone, Axial/Radial Logo Printing | Titanium Dioxide (TiO2) free available upon request |
| Finished Packaging Types | HDPE Bottles, Amber Glass Jars, Alu-PVC / Alu-Alu Blister Packs, Bulk Carton Polybags, Multi-serving Pouches | Induction sealed, tamper-evident neck bands, child-resistant caps |
| Standard Minimum Order | 100 Bottles (Private Label Ready) / 50,000 Capsules (Custom Blend OEM) | Factory direct batch pricing, export logistics ready |
| Quality Release Documents | Certificate of Analysis (COA), Allergen Statement, Heavy Metal Report, Microbe Test, BSE/TSE-Free Statement | TÜV Rheinland verified facility, ISO 22000, HACCP |
Frequently Asked Questions by Capsule Buyers
Essential details to guide your procurement, formulation formulation, and custom packaging decisions.
What capsule shell options are available for vegan or clean-label brands?
Shaanxi ESNO Biotech Co., Ltd. specializes in clean-label capsule development. We supply USP-grade Vegetarian HPMC (derived from pine wood cellulose), natural plant fermented Pullulan, and delayed-release acid-resistant vegan shells. All vegan shells are non-GMO, gluten-free, allergen-free, Halal and Kosher certified, with 100% Titanium Dioxide (TiO2) free opacity options.
Can you formulate a proprietary capsule blend from our ingredient brief?
Yes. Our in-house R&D team has formulated over 400 unique dietary supplements. Simply supply your target actives, desired potencies, and functional claims (e.g. cognitive support, liver detoxification, athletic energy). We will evaluate powder flowability, bulk density, excipient suitability (such as organic rice flour or silica), produce pilot samples for your evaluation, and scale to commercial production.
What are the lead times for custom capsule production and private labeling?
Stock formulations packaged with custom printed labels can typically be dispatched in 10 to 15 business days. Custom ingredient sourcing, custom encapsulation, and complete bespoke printed blister/box runs typically require 3 to 4 weeks depending on raw material availability and testing protocols.
How does Shaanxi ESNO Biotech Co., Ltd. manage heavy metal and microbiological safety?
Every ingredient undergoes mandatory quarantine and testing via Inductively Coupled Plasma Mass Spectrometry (ICP-MS) for Lead (Pb), Arsenic (As), Cadmium (Cd), and Mercury (Hg) to comply with FDA, USP <2232>, and EU food supplement safety laws. Microbiological integrity is systematically verified in our internal laboratory incubator and verified with third-party reports upon client request.
Can you assist with label design compliance and Amazon FBA preparation?
Yes. We offer turnkey packaging solutions including label layout compliance review (Supplement Facts layout, Net Quantity declarations, allergen advisories), bottle induction sealing, barcoding, shrink banding, master carton drop-testing, and Amazon FBA pallet preparation.
Ready to Manufacture Your Custom Hard Capsule Line?
Get in touch with Shaanxi ESNO Biotech Co., Ltd.'s formulation specialists. Receive batch feasibility feedback, technical specifications, and factory-direct pricing within 24 hours.